The park contains one of the most exciting faunas of any Ugandan national park. Along with the neighboring Karamoja region, it houses many species found nowhere else in Uganda, including the greater and lesser kudu, eland and cheetah. Carnivores here include the lion, leopard, spotted hyena and black-backed and side-striped jackals. Other large species regularly seen here are elephant, Burchell’s zebra, bushpig, warthog, Rothschild’s giraffe, Cape buffalo, bushbuck, bushduiker, Defassa waterbuck, Bohor reedbuck, Jackson’s hartebeest and oribi.
The park boasts an extensive bird list of around 475 species, making it second only in Uganda to Queen Elizabeth National Park. A few species of note are the Ostrich, Kori Bustard and Karamoja Apalis.
Kidepo is notable for its birds of prey. Of the 56 species recorded, 14 – including Verreaux’s Eagle, Egyptian Vulture and Pygmy Falcon – are believed to be endemic to the Kidepo and Karamoja region. There has, however, been no comprehensive survey of birds in Kidepo and visitors stand a good chance of adding to the current list.